Characterization of liver lymphomyeloid cells in mice infected with Plasmodium yoelii sporozoites.
P Faure, M Marussig, P Goossens, F Miltgen… - Immunology, 1994 - ncbi.nlm.nih.gov
P Faure, M Marussig, P Goossens, F Miltgen, D Mazier
Immunology, 1994•ncbi.nlm.nih.govWe have isolated, characterized and quantified the immunocompetent cells present in the
extravascular hepatic compartment at various stages after Plasmodium yoelii malaria
infection with sporozoites. Cytological analyses revealed a predominantly lymphoid
population. In mice with a primary infection, the predominant cells were CD4+, CD8+ and B
lymphocytes. In fully protected mice, CD3+ CD4-CD8-and polymorphonuclear cells,
particularly eosinophils, were most common. The significance of changes in subpopulations …
extravascular hepatic compartment at various stages after Plasmodium yoelii malaria
infection with sporozoites. Cytological analyses revealed a predominantly lymphoid
population. In mice with a primary infection, the predominant cells were CD4+, CD8+ and B
lymphocytes. In fully protected mice, CD3+ CD4-CD8-and polymorphonuclear cells,
particularly eosinophils, were most common. The significance of changes in subpopulations …
Abstract
We have isolated, characterized and quantified the immunocompetent cells present in the extravascular hepatic compartment at various stages after Plasmodium yoelii malaria infection with sporozoites. Cytological analyses revealed a predominantly lymphoid population. In mice with a primary infection, the predominant cells were CD4+, CD8+ and B lymphocytes. In fully protected mice, CD3+ CD4-CD8-and polymorphonuclear cells, particularly eosinophils, were most common. The significance of changes in subpopulations is discussed in relation to antigen presentation and host-protective mechanisms.
ncbi.nlm.nih.gov
