Newborn primary congenital glaucoma: histopathologic features of the anterior chamber filtration angle

LP Perry, FA Jakobiec, FR Zakka, DS Walton - Journal of American …, 2012 - Elsevier
We present histopathologic findings that have not been previously reported as associated
with abnormalities of the anterior chamber angle underlying newborn primary congenital
glaucoma as a distinct entity. The major histopathologic findings were partial absence and
retrodisplacement of Schlemm's canal, hypoplasia of the trabecular meshwork, broad
attachment of ciliary muscle to the meshwork, and anterior insertion of hypoplastic iris with
the formation of a pseudomembrane. These profound anatomic derangements explain why …