[CITATION][C] Significance of C-type natriuretic peptide (CNP) in endochondral ossification: analysis of CNP knockout mice
Y Komatsu, H Chusho, N Tamura, A Yasoda… - Journal of bone and …, 2002 - Springer
Journal of bone and mineral metabolism, 2002•Springer
We cloned mouse and human CNP genes [6, 7]. The mouse CNP gene is composed of at
least two exons and one intron. The 5-flanking region contains an array of cis-acting
regulatory elements, including Y box, GC box, and a CRE-like sequence, as well as a
dinucleotide CA repeat (microsatellite). On the basis of polymerase chain reaction (PCR)-
analyzed microsatellite-length polymorphisms among recombinant inbred strains of mice,
the CNP gene (Nppc) was assigned to mouse chromosome 1 (cen-Acrg-0.79 0.82 c M …
least two exons and one intron. The 5-flanking region contains an array of cis-acting
regulatory elements, including Y box, GC box, and a CRE-like sequence, as well as a
dinucleotide CA repeat (microsatellite). On the basis of polymerase chain reaction (PCR)-
analyzed microsatellite-length polymorphisms among recombinant inbred strains of mice,
the CNP gene (Nppc) was assigned to mouse chromosome 1 (cen-Acrg-0.79 0.82 c M …
We cloned mouse and human CNP genes [6, 7]. The mouse CNP gene is composed of at least two exons and one intron. The 5-flanking region contains an array of cis-acting regulatory elements, including Y box, GC box, and a CRE-like sequence, as well as a dinucleotide CA repeat (microsatellite). On the basis of polymerase chain reaction (PCR)-analyzed microsatellite-length polymorphisms among recombinant inbred strains of mice, the CNP gene (Nppc) was assigned to mouse chromosome 1 (cen-Acrg-0.79 0.82 c M-Nppcl (Sag)
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