[PDF][PDF] Nutropioids, hedonism in the gut?

PT Pfluger, SC Schriever, MH Tschöp - Cell metabolism, 2012 - cell.com
PT Pfluger, SC Schriever, MH Tschöp
Cell metabolism, 2012cell.com
The opioid system plays a pivotal role in how our brain regulates hedonic components of
ingestive behavior. Duraffourd et al.(2012) add the gut to this opioid landscape,
demonstrating direct activation of periportal μ-opioid receptors by food-derived opioid
peptides (nutropioids), and a gut-brain feedback spiral that culminates in enhanced satiety.
The opioid system plays a pivotal role in how our brain regulates hedonic components of ingestive behavior. Duraffourd et al. (2012) add the gut to this opioid landscape, demonstrating direct activation of periportal μ-opioid receptors by food-derived opioid peptides (nutropioids), and a gut-brain feedback spiral that culminates in enhanced satiety.
cell.com