P2X7 receptor is expressed in human vessels and might play a role in atherosclerosis
M Piscopiello, M Sessa… - International …, 2013 - internationaljournalofcardiology.com
ATP-activated purinergic receptor channel type P2X7 (P2X7) is implicated in a broad range
of biological responses, such as the inflammatory response of circulating cells and possibly
the trigger and propagation of coagulation [1]. Increasing evidences support the involvement
of P2X7 and related molecules in the cardiovascular regulation [2], however their expression
and role in human vasculature and in atherosclerosis have been poorly investigated [3]. We
studied P2X7–ATP pathway by microscopy and immunochemical methods on a series of …
of biological responses, such as the inflammatory response of circulating cells and possibly
the trigger and propagation of coagulation [1]. Increasing evidences support the involvement
of P2X7 and related molecules in the cardiovascular regulation [2], however their expression
and role in human vasculature and in atherosclerosis have been poorly investigated [3]. We
studied P2X7–ATP pathway by microscopy and immunochemical methods on a series of …