Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1
M Taketo, M Matsui, JM Rochelle, J Yodoi, MF Seldin - Genomics, 1994 - Elsevier
M Taketo, M Matsui, JM Rochelle, J Yodoi, MF Seldin
Genomics, 1994•ElsevierThioredoxins are involved in various biochemical systems and mediate both redox and
nonredox functions. In mammalian cells, thioredoxin functions as an endogenous
glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF)
that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I
transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed
pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn …
nonredox functions. In mammalian cells, thioredoxin functions as an endogenous
glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF)
that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I
transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed
pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn …
Abstract
Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.
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