[HTML][HTML] Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?

P Newsholme - The Journal of nutrition, 2001 - Elsevier
Glutamine is normally considered to be a nonessential amino acid. However, recent studies
have provided evidence that glutamine may become “conditionally essential” during
inflammatory conditions such as infection and injury. It is now well documented that under
appropriate conditions, glutamine is essential for cell proliferation, that it can act as a
respiratory fuel and that it can enhance the function of stimulated immune cells. Studies thus
far have determined the effect of extracellular glutamine concentration on lymphocyte …