The effects of IL-6 on CD4 T cell responses
O Dienz, M Rincon - Clinical immunology, 2009 - Elsevier
Cytokines have long been known to profoundly influence the adaptive immune response by
determining CD4 T cell differentiation. Although IL-6 has been initially characterized as a B
cell growth factor and inducer of antibody production research from our lab and others has
revealed over the last years that IL-6 also plays a significant role in CD4 T cell differentiation.
This review highlights the variety of ways in which IL-6 affects CD4 effector functions and
how this may contribute to different types of diseases.
determining CD4 T cell differentiation. Although IL-6 has been initially characterized as a B
cell growth factor and inducer of antibody production research from our lab and others has
revealed over the last years that IL-6 also plays a significant role in CD4 T cell differentiation.
This review highlights the variety of ways in which IL-6 affects CD4 effector functions and
how this may contribute to different types of diseases.