Linking mitochondrial dynamics, cristae remodeling and supercomplex formation: How mitochondrial structure can regulate bioenergetics
N Baker, J Patel, M Khacho - Mitochondrion, 2019 - Elsevier
The dynamic and fluid nature of mitochondria allows for modifications in mitochondrial
shape, connectivity and cristae architecture. The precise balance of mitochondrial dynamics
is among the most critical features in the control of mitochondrial function. In the past few
years, mitochondrial shape has emerged as a key regulatory factor in the determination of
the bioenergetic capacity of cells. This is mostly due to the recent discoveries linking
changes in cristae organization with supercomplex assembly of the electron transport chain …
shape, connectivity and cristae architecture. The precise balance of mitochondrial dynamics
is among the most critical features in the control of mitochondrial function. In the past few
years, mitochondrial shape has emerged as a key regulatory factor in the determination of
the bioenergetic capacity of cells. This is mostly due to the recent discoveries linking
changes in cristae organization with supercomplex assembly of the electron transport chain …
