[HTML][HTML] T cells doing it for themselves: TGF-β regulation of Th1 and Th17 cells

MJ McGeachy, DJ Cua - Immunity, 2007 - cell.com
Immunity, 2007cell.com
The source of TGF-β, which regulates inflammation in various disease settings, is unclear. In
this issue of Immunity, Li et al.(2007) find that not only does T cell-produced TGF-β regulate
Th1-cell-mediated inflammation, but it is also required for the generation of Th17 cells in
vivo.
The source of TGF-β, which regulates inflammation in various disease settings, is unclear. In this issue of Immunity, Li et al. (2007) find that not only does T cell-produced TGF-β regulate Th1-cell-mediated inflammation, but it is also required for the generation of Th17 cells in vivo.
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