Origin of scalp vertex aplasia cutis

MJ Stephan, DW Smith, JW Ponzi, ER Alden - The Journal of Pediatrics, 1982 - Elsevier
MJ Stephan, DW Smith, JW Ponzi, ER Alden
The Journal of Pediatrics, 1982Elsevier
Six children with uncomplicated scalp vertex aplasia cutis from birth are discussed. The
vertex parietal hair whorl represents the scalp surface area under greatest tension from the
hemispheric growth of underlying brain during early embryogenesis. It is hypothesized that
this predominant location of aplasia cutis is related to those disruptive biomechanical forces
of stretching. Genetic factors may predispose to the development of the lesion in some
cases. Histologic examination of the scalp lesions reflects overstretching.
Six children with uncomplicated scalp vertex aplasia cutis from birth are discussed. The vertex parietal hair whorl represents the scalp surface area under greatest tension from the hemispheric growth of underlying brain during early embryogenesis. It is hypothesized that this predominant location of aplasia cutis is related to those disruptive biomechanical forces of stretching. Genetic factors may predispose to the development of the lesion in some cases. Histologic examination of the scalp lesions reflects overstretching.
Elsevier